Predictions › United States › Arizona Cardinals vs Kansas City Chiefs

NFLSun 22 Nov, 13:00 United States time

Arizona Cardinals vs Kansas City Chiefs prediction

Arrowhead Stadium

Arizona CardinalsAway

15.3 : 27.7

projected points

Kansas City ChiefsHome

15%Cardinals

85%Chiefs

Eagle safe pickChiefs to win

-1000

Quick answer

Our prediction for Arizona Cardinals vs Kansas City Chiefs is Kansas City Chiefs to win, with a 85% chance. We project Arizona Cardinals 15.3 and Kansas City Chiefs 27.7. Our best bet is Chiefs to win at -1000.

Prediction: Kansas City Chiefs to win
Chance: 85%
Projected score: Arizona Cardinals 15, Kansas City Chiefs 28
Projected total: 43.0 points
Best bet: Chiefs to win at -1000

Note: This is our view from the numbers, not a sure thing. One injury, one turnover or one late score can change any game.

The eagle's three picks

✓

Eagle safe pick

Chiefs to win

85% chancePrice -10001 unit

Note: Safe is the bet most likely to win. Value is where the price pays more than it should. Bold pays more but loses more often. A unit is your normal stake.

Why we think this

1
What our numbers say
The model gives Kansas City Chiefs 85% and Arizona Cardinals 15%. The bookmakers agree and make Kansas City Chiefs the favourite at -1000.
2
Recent form
Kansas City Chiefs won 3 of their last 5 and Arizona Cardinals won 2 of their last 5. Kansas City Chiefs come in with the better run.
3
Home and away
Kansas City Chiefs won 5 of their last 10 games at home. Arizona Cardinals won 4 of their last 12 on the road.
4
Scoring
Kansas City Chiefs score 19.3 points a game and let in 19.3. Arizona Cardinals score 20.9 and let in 30.5. Their recent games average 38.5 and 51.4 points in total, and the market line is 42.5.
5
The safest bet
Chiefs to win has a 85% chance, the highest of the bets worth taking here.

Note: Every reason here comes from real results and real prices. We do not guess and we do not copy tipsters.

What moved our number

Eagle 2.0 starts from results and prices, then reads four more things. Here is every change it made on this game.

Nothing moved this one. Both teams are rested, form is level and there is no team news we can act on, so the number is what the results and the price say on their own.

Corrected using our own settled bets

Note: Each reading is capped on purpose. Together they can never move an expected goal number by more than 12 percent. See the full method.

Match preview

Arizona Cardinals vs Kansas City Chiefs: Kansas City Chiefs are favourites

By the EagleEyeOdds desk

The big picture

Kansas City Chiefs host Arizona Cardinals in the NFL on Sun 22 Nov, 13:00 at Arrowhead Stadium. Our prediction for Arizona Cardinals vs Kansas City Chiefs is Kansas City Chiefs to win, with a 85% chance. We project Arizona Cardinals 15.3 and Kansas City Chiefs 27.7. Our best bet is Chiefs to win at -1000.

Kansas City Chiefs form

Kansas City Chiefs have 7 wins and 12 losses in their last 20 games, with 386 points scored and 385 conceded. At home they have 5 wins and 4 losses from 10. Their last 5 results read W, L, L, W, W, newest first.

Arizona Cardinals form

Arizona Cardinals have 4 wins and 16 losses in their last 20 games, with 417 points scored and 610 conceded. Away from home they have 4 wins and 8 losses from 12. Their last 5 results read L, W, L, W, L, newest first.

Our call

We expect Arizona Cardinals to score about 15.3 points and Kansas City Chiefs about 27.7. That points to Kansas City Chiefs to win. Our safest bet is Chiefs to win at -1000.

Note: This preview is written from our data and updates as new results and prices come in.

Team records

Last 20 games in all competitions.

	Chiefs	Cardinals
Games played	20	20
Wins	7	4
Losses	12	16
Points scored	386	417
Points conceded	385	610
Scored per game	19.3	20.9
Conceded per game	19.3	30.5
Home record	5W 4L	0W 8L
Away record	2W 8L	4W 8L

Note: W is a win and L a loss. A team with more games at home or away can look better or worse than it is.

Price check against Draft Kings

Bet	Our chance	Fair	Price	Value
Chiefs to win	85%	-589	-1000	-6.0%
Cardinals to win	13%	+662	+650	-1.6%
Chiefs -14	43%	+133	-110	-18.0%
Cardinals +14	50%	-101	-110	-4.0%
Over 42.5 points	48%	+109	-105	-6.7%
Under 42.5 points	45%	+120	-115	-15.1%

Note: Green value means the price pays more than our fair price. We only call it a value pick from 3% up, because small gaps can be noise.

Spread and total at every line

Chiefs spread	Covers	Fair
Chiefs -19.5	30%	+234
Chiefs -15.5	41%	+144
Chiefs -12.5	50%	+101
Chiefs -9.5	59%	-141
Chiefs -5.5	70%	-229

Total points	Over	Under
36.5	69%	31%
40.5	58%	42%
43.5	49%	51%
46.5	39%	61%
50.5	28%	72%

Note: A spread gives one team a head start. Chiefs +3.5 wins if Chiefs win or lose by 3 or fewer. If the result lands exactly on the line, your stake comes back.

Latest news on these teams

All news

NFL

Arizona Cardinals Name Carson Beck Starting Quarterback Against Rams

Rookie Carson Beck will start at quarterback for the Arizona Cardinals on Sunday against the Los Angeles Rams following an arm injury to Gardner Minshew.

11 Nov 2026

NFL

Josh Downs Reacts to Kansas City Chiefs Trade After Leaving Colts

Josh Downs expressed his feelings about joining the Kansas City Chiefs using a famous Vince Carter GIF after requesting a trade from Indy.

10 Nov 2026

NFL

Chiefs Avoid QB Sneak as Short Yardage Struggles Continue

Kansas City is struggling on short-yardage plays while avoiding quarterback sneaks entirely this season.

4 Nov 2026

Questions people ask

Who will win Arizona Cardinals vs Kansas City Chiefs?

What is the projected score for Arizona Cardinals vs Kansas City Chiefs?

We project Arizona Cardinals 15.3 and Kansas City Chiefs 27.7, about 43.0 points in total.

How are Kansas City Chiefs playing?

How are Arizona Cardinals playing?

What is the best bet for Arizona Cardinals vs Kansas City Chiefs?

Chiefs to win at -1000, with a 85% chance.

Note: Answers change as prices move. We check every game again every 30 minutes.

Important, please read before you bet

These are opinions, not results. Everything on this page is a probability worked out by a computer model from past games and current prices. No one can know what will happen in Chiefs against Cardinals. A pick at 70 percent still loses about 3 times in every 10.
We do not promise profit. Our public record shows wins and losses together, and losing runs happen to every method. Treat any money you stake as money you may never see again.
18 plus only. Betting is for adults. In some countries the legal age is higher and in some it is not allowed at all. You alone are responsible for checking the law where you live.
Prices move. The odds shown were read from a bookmaker feed and may already be different. Always check the price in your own account before you place anything.
No advice for your money. We are not financial advisers and we do not know your situation. Nothing here is financial advice or a recommendation to stake any amount.
Betting can harm you. If it stops being fun, if you chase losses, or if you hide it from people close to you, stop and get help. Free and private support is available from BeGambleAware, GamCare and Gamblers Anonymous. Read our responsible gambling page for tools that block betting sites.

Full terms are on our disclaimer and terms pages.

Note: Never stake money you need for rent, food, bills or anyone who depends on you.