Predictions › United States › Minnesota Vikings vs San Francisco 49ers

NFLSun 22 Nov, 20:20 United States time

Minnesota Vikings vs San Francisco 49ers prediction

Estadio Banorte

Minnesota VikingsAway

19.6 : 24.0

projected points

San Francisco 49ersHome

39%Vikings

61%49ers

Eagle safe pickUnder 52.5 points

-315

Quick answer

Our prediction for Minnesota Vikings vs San Francisco 49ers is San Francisco 49ers to win, with a 61% chance. We project Minnesota Vikings 19.6 and San Francisco 49ers 24.0. Our best bet is Under 52.5 points at -315.

Prediction: San Francisco 49ers to win
Chance: 61%
Projected score: Minnesota Vikings 20, San Francisco 49ers 24
Projected total: 43.6 points
Best bet: Under 52.5 points at -315

Note: This is our view from the numbers, not a sure thing. One injury, one turnover or one late score can change any game.

The eagle's three picks

✓

Eagle safe pick

Under 52.5 points

76% chanceFair price -3152 units

⚡

Eagle bold pick

Vikings to win

35% chancePrice +1701 unit

Note: Safe is the bet most likely to win. Value is where the price pays more than it should. Bold pays more but loses more often. A unit is your normal stake.

Why we think this

1
What our numbers say
The model gives San Francisco 49ers 61% and Minnesota Vikings 39%. The bookmakers agree and make San Francisco 49ers the favourite at -205.
2
Recent form
San Francisco 49ers won 4 of their last 5 and Minnesota Vikings won 3 of their last 5. San Francisco 49ers come in with the better run.
3
Home and away
San Francisco 49ers won 8 of their last 10 games at home. Minnesota Vikings won 6 of their last 10 on the road.
4
Scoring
San Francisco 49ers score 27.6 points a game and let in 20.3. Minnesota Vikings score 16.5 and let in 16.0. Their recent games average 47.9 and 32.5 points in total, and the market line is 45.5.
5
The safest bet
Under 52.5 points has a 76% chance, the highest of the bets worth taking here.

Note: Every reason here comes from real results and real prices. We do not guess and we do not copy tipsters.

What moved our number

Eagle 2.0 starts from results and prices, then reads four more things. Here is every change it made on this game.

Nothing moved this one. Both teams are rested, form is level and there is no team news we can act on, so the number is what the results and the price say on their own.

Corrected using our own settled bets

Note: Each reading is capped on purpose. Together they can never move an expected goal number by more than 12 percent. See the full method.

Match preview

Minnesota Vikings vs San Francisco 49ers: San Francisco 49ers are favourites

By the EagleEyeOdds desk

The big picture

San Francisco 49ers host Minnesota Vikings in the NFL on Sun 22 Nov, 20:20 at Estadio Banorte. Our prediction for Minnesota Vikings vs San Francisco 49ers is San Francisco 49ers to win, with a 61% chance. We project Minnesota Vikings 19.6 and San Francisco 49ers 24.0. Our best bet is Under 52.5 points at -315.

San Francisco 49ers form

San Francisco 49ers have 16 wins and 4 losses in their last 20 games, with 553 points scored and 405 conceded. At home they have 8 wins and 2 losses from 10. Their last 5 results read W, L, W, W, W, newest first.

Minnesota Vikings form

Minnesota Vikings have 12 wins and 8 losses in their last 20 games, with 330 points scored and 320 conceded. Away from home they have 6 wins and 4 losses from 10. Their last 5 results read L, L, W, W, W, newest first.

Our call

We expect Minnesota Vikings to score about 19.6 points and San Francisco 49ers about 24.0. That points to San Francisco 49ers to win. Our safest bet is Under 52.5 points at -315. Our bold bet is Vikings to win at +170.

Note: This preview is written from our data and updates as new results and prices come in.

Team records

Last 20 games in all competitions.

	49ers	Vikings
Games played	20	20
Wins	16	12
Losses	4	8
Points scored	553	330
Points conceded	405	320
Scored per game	27.6	16.5
Conceded per game	20.3	16.0
Home record	8W 2L	6W 4L
Away record	8W 2L	6W 4L

Note: W is a win and L a loss. A team with more games at home or away can look better or worse than it is.

Price check against Draft Kings

Bet	Our chance	Fair	Price	Value
49ers to win	61%	-157	-205	-9.1%
Vikings to win	35%	+184	+170	-5.1%
49ers -3.5	49%	+106	-115	-9.3%
Vikings +3.5	45%	+124	-105	-12.8%
Over 45.5 points	42%	+137	-115	-21.2%
Under 45.5 points	51%	-104	-105	-0.3%

Note: Green value means the price pays more than our fair price. We only call it a value pick from 3% up, because small gaps can be noise.

Spread and total at every line

49ers spread	Covers	Fair
49ers -11.5	30%	+235
49ers -7.5	41%	+145
49ers -4.5	50%	+102
49ers -1.5	58%	-140
49ers +2.5	69%	-227

Total points	Over	Under
36.5	71%	29%
40.5	59%	41%
43.5	50%	50%
46.5	41%	59%
50.5	30%	70%

Note: A spread gives one team a head start. 49ers +3.5 wins if 49ers win or lose by 3 or fewer. If the result lands exactly on the line, your stake comes back.

Latest news on these teams

All news

NFL

Kirk Cousins Takes Control In First Day Back With Vikings

Kirk Cousins returned to practice with the Minnesota Vikings on Thursday after being acquired from the Las Vegas Raiders.

4 hours ago

NFL

Keenan Allen Energized After Surprise Trade to San Francisco

Keenan Allen joins the San Francisco 49ers following a surprise trade from the Indianapolis Colts.

12 Nov 2026

NFL

Kirk Cousins Returns to Minnesota After Phone Call With Kevin O'Connell

Kirk Cousins has rejoined the Minnesota Vikings after a phone call with coach Kevin O'Connell convinced him to accept a trade from Las Vegas.

12 Nov 2026

Questions people ask

Who will win Minnesota Vikings vs San Francisco 49ers?

What is the projected score for Minnesota Vikings vs San Francisco 49ers?

We project Minnesota Vikings 19.6 and San Francisco 49ers 24.0, about 43.6 points in total.

How are San Francisco 49ers playing?

How are Minnesota Vikings playing?

What is the best bet for Minnesota Vikings vs San Francisco 49ers?

Under 52.5 points at -315, with a 76% chance.

Note: Answers change as prices move. We check every game again every 30 minutes.

Important, please read before you bet

These are opinions, not results. Everything on this page is a probability worked out by a computer model from past games and current prices. No one can know what will happen in 49ers against Vikings. A pick at 70 percent still loses about 3 times in every 10.
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