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Predictions › United States › Buffalo Bills vs Los Angeles Rams
NFLMon 12 Oct, 20:15 United States time

Buffalo Bills vs Los Angeles Rams prediction

SoFi Stadium

Buffalo BillsAway
24.4 : 27.0
projected points
Los Angeles RamsHome
47%Bills
53%Rams
Eagle safe pickUnder 59.5 points
-303

Quick answer

Our prediction for Buffalo Bills vs Los Angeles Rams is Los Angeles Rams to win, with a 53% chance, but it is a close call. We project Buffalo Bills 24.4 and Los Angeles Rams 27.0. Our best bet is Under 59.5 points at -303.

Prediction
Los Angeles Rams to win
Chance
53%
Projected score
Buffalo Bills 24, Los Angeles Rams 27
Projected total
51.4 points
Best bet
Under 59.5 points at -303

Note: This is our view from the numbers, not a sure thing. One injury, one turnover or one late score can change any game.

The eagle's three picks

✓

Eagle safe pick

Under 59.5 points
75% chanceFair price -3032 units

Note: Safe is the bet most likely to win. Value is where the price pays more than it should. Bold pays more but loses more often. A unit is your normal stake.

Why we think this

  1. 1
    What our numbers say

    The model gives Los Angeles Rams 53% and Buffalo Bills 47%. The bookmakers agree and make Los Angeles Rams the favourite at -135.

  2. 2
    Recent form

    Los Angeles Rams won 3 of their last 5 and Buffalo Bills won 5 of their last 5. Buffalo Bills come in with the better run.

  3. 3
    Home and away

    Los Angeles Rams won 7 of their last 8 games at home. Buffalo Bills won 7 of their last 11 on the road.

  4. 4
    Scoring

    Los Angeles Rams score 29.7 points a game and let in 20.4. Buffalo Bills score 28.7 and let in 21.8. Their recent games average 50.1 and 50.5 points in total, and the market line is 52.5.

  5. 5
    The safest bet

    Under 59.5 points has a 75% chance, the highest of the bets worth taking here.

Note: Every reason here comes from real results and real prices. We do not guess and we do not copy tipsters.

What moved our number

Eagle 2.0 starts from results and prices, then reads four more things. Here is every change it made on this game.
  • Ramsteam news-1%
Corrected using our own settled bets

Note: Each reading is capped on purpose. Together they can never move an expected goal number by more than 12 percent. See the full method.

Match preview

Buffalo Bills vs Los Angeles Rams: Los Angeles Rams shade it

By the EagleEyeOdds desk

The big picture

Los Angeles Rams host Buffalo Bills in the NFL on Mon 12 Oct, 20:15 at SoFi Stadium. Our prediction for Buffalo Bills vs Los Angeles Rams is Los Angeles Rams to win, with a 53% chance, but it is a close call. We project Buffalo Bills 24.4 and Los Angeles Rams 27.0. Our best bet is Under 59.5 points at -303.

Los Angeles Rams form

Los Angeles Rams have 14 wins and 6 losses in their last 20 games, with 594 points scored and 408 conceded. At home they have 7 wins and 1 loss from 8. Their last 5 results read L, W, L, W, W, newest first.

Buffalo Bills form

Buffalo Bills have 15 wins and 5 losses in their last 20 games, with 574 points scored and 435 conceded. Away from home they have 7 wins and 4 losses from 11. Their last 5 results read W, W, W, W, W, newest first.

Our call

We expect Buffalo Bills to score about 24.4 points and Los Angeles Rams about 27.0. That points to Los Angeles Rams to win. Our safest bet is Under 59.5 points at -303.

Note: This preview is written from our data and updates as new results and prices come in.

Team records

Last 20 games in all competitions.

RamsBills
Games played2020
Wins1415
Losses65
Points scored594574
Points conceded408435
Scored per game29.728.7
Conceded per game20.421.8
Home record7W 1L8W 1L
Away record7W 5L7W 4L

Note: W is a win and L a loss. A team with more games at home or away can look better or worse than it is.

Price check against Draft Kings

BetOur chanceFairPriceValue
Rams to win53%-111-135-8.3%
Bills to win41%+141+114-11.4%
Rams -2.547%+112-110-10.0%
Bills +2.547%+113-110-10.4%
Over 52.5 points44%+128-110-16.2%
Under 52.5 points50%-101-110-4.2%

Note: Green value means the price pays more than our fair price. We only call it a value pick from 3% up, because small gaps can be noise.

Spread and total at every line

Rams spreadCoversFair
Rams -9.530%+230
Rams -5.541%+142
Rams -2.550%-101
Rams +0.559%-143
Rams +4.570%-232
Total pointsOverUnder
44.570%30%
48.559%41%
51.550%50%
54.541%59%
58.529%71%

Note: A spread gives one team a head start. Rams +3.5 wins if Rams win or lose by 3 or fewer. If the result lands exactly on the line, your stake comes back.

Latest news on these teams

All news
NFL

Buffalo Bills Survive Five Turnovers to Beat Chargers 24-16

Despite committing five turnovers, the Buffalo Bills improved to 3-0 with a gritty 24-16 victory over the Los Angeles Chargers.

28 Sept 2026
NFL

Rams Pass Rusher Myles Garrett Faces Six Week Recovery After Knee Surgery

Los Angeles Rams star Myles Garrett is expected to miss about six weeks following knee surgery, potentially delaying his return until early November.

27 Sept 2026
NFL

Stafford and Adams Spark Rams in Dominant Win Over Injured Giants

Matthew Stafford and Davante Adams shined for the Rams in a 28-6 win while the Giants lost quarterback Jaxson Dart to an early injury.

22 Sept 2026

Questions people ask

Who will win Buffalo Bills vs Los Angeles Rams?

Our prediction for Buffalo Bills vs Los Angeles Rams is Los Angeles Rams to win, with a 53% chance, but it is a close call. We project Buffalo Bills 24.4 and Los Angeles Rams 27.0. Our best bet is Under 59.5 points at -303.

What is the projected score for Buffalo Bills vs Los Angeles Rams?

We project Buffalo Bills 24.4 and Los Angeles Rams 27.0, about 51.4 points in total.

How are Los Angeles Rams playing?

Los Angeles Rams have 14 wins and 6 losses in their last 20 games, with 594 points scored and 408 conceded. At home they have 7 wins and 1 loss from 8. Their last 5 results read L, W, L, W, W, newest first.

How are Buffalo Bills playing?

Buffalo Bills have 15 wins and 5 losses in their last 20 games, with 574 points scored and 435 conceded. Away from home they have 7 wins and 4 losses from 11. Their last 5 results read W, W, W, W, W, newest first.

What is the best bet for Buffalo Bills vs Los Angeles Rams?

Under 59.5 points at -303, with a 75% chance.

Note: Answers change as prices move. We check every game again every 30 minutes.

Important, please read before you bet

  • These are opinions, not results. Everything on this page is a probability worked out by a computer model from past games and current prices. No one can know what will happen in Rams against Bills. A pick at 70 percent still loses about 3 times in every 10.
  • We do not promise profit. Our public record shows wins and losses together, and losing runs happen to every method. Treat any money you stake as money you may never see again.
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