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Predictions › United States › Detroit Lions vs Arizona Cardinals
NFLSun 11 Oct, 16:25 United States time

Detroit Lions vs Arizona Cardinals prediction

State Farm Stadium

Detroit LionsAway
29.1 : 23.0
projected points
Arizona CardinalsHome
69%Lions
31%Cardinals
Eagle safe pickLions to win
-245

Quick answer

Our prediction for Detroit Lions vs Arizona Cardinals is Detroit Lions to win, with a 69% chance. We project Detroit Lions 29.1 and Arizona Cardinals 23.0. Our best bet is Lions to win at -245.

Prediction
Detroit Lions to win
Chance
69%
Projected score
Detroit Lions 29, Arizona Cardinals 23
Projected total
52.1 points
Best bet
Lions to win at -245

Note: This is our view from the numbers, not a sure thing. One injury, one turnover or one late score can change any game.

The eagle's three picks

✓

Eagle safe pick

Lions to win
69% chancePrice -2451 unit

Note: Safe is the bet most likely to win. Value is where the price pays more than it should. Bold pays more but loses more often. A unit is your normal stake.

Why we think this

  1. 1
    What our numbers say

    The model gives Arizona Cardinals 31% and Detroit Lions 69%. The bookmakers agree and make Detroit Lions the favourite at -245.

  2. 2
    Recent form

    Arizona Cardinals won 1 of their last 5 and Detroit Lions won 4 of their last 5. Detroit Lions come in with the better run.

  3. 3
    Home and away

    Arizona Cardinals won 0 of their last 9 games at home. Detroit Lions won 4 of their last 10 on the road.

  4. 4
    Scoring

    Arizona Cardinals score 22.2 points a game and let in 30.9. Detroit Lions score 26.4 and let in 23.8. Their recent games average 53.1 and 50.1 points in total, and the market line is 52.5.

  5. 5
    The safest bet

    Lions to win has a 69% chance, the highest of the bets worth taking here.

Note: Every reason here comes from real results and real prices. We do not guess and we do not copy tipsters.

What moved our number

Eagle 2.0 starts from results and prices, then reads four more things. Here is every change it made on this game.

Nothing moved this one. Both teams are rested, form is level and there is no team news we can act on, so the number is what the results and the price say on their own.

Corrected using our own settled bets

Note: Each reading is capped on purpose. Together they can never move an expected goal number by more than 12 percent. See the full method.

Match preview

Detroit Lions vs Arizona Cardinals: Detroit Lions are favourites

By the EagleEyeOdds desk

The big picture

Arizona Cardinals host Detroit Lions in the NFL on Sun 11 Oct, 16:25 at State Farm Stadium. Our prediction for Detroit Lions vs Arizona Cardinals is Detroit Lions to win, with a 69% chance. We project Detroit Lions 29.1 and Arizona Cardinals 23.0. Our best bet is Lions to win at -245.

Arizona Cardinals form

Arizona Cardinals have 3 wins and 17 losses in their last 20 games, with 444 points scored and 618 conceded. At home they have 0 wins and 9 losses from 9. Their last 5 results read L, L, W, L, L, newest first.

Detroit Lions form

Detroit Lions have 11 wins and 9 losses in their last 20 games, with 527 points scored and 475 conceded. Away from home they have 4 wins and 6 losses from 10. Their last 5 results read W, L, W, W, W, newest first.

Our call

We expect Detroit Lions to score about 29.1 points and Arizona Cardinals about 23.0. That points to Detroit Lions to win. Our safest bet is Lions to win at -245.

Note: This preview is written from our data and updates as new results and prices come in.

Team records

Last 20 games in all competitions.

CardinalsLions
Games played2020
Wins311
Losses179
Points scored444527
Points conceded618475
Scored per game22.226.4
Conceded per game30.923.8
Home record0W 9L7W 3L
Away record3W 8L4W 6L

Note: W is a win and L a loss. A team with more games at home or away can look better or worse than it is.

Price check against Draft Kings

BetOur chanceFairPriceValue
Cardinals to win31%+224+200-7.3%
Lions to win69%-224-245-2.7%
Cardinals +5.545%+121-110-13.6%
Lions -5.549%+105-110-6.8%
Over 52.5 points46%+118-110-12.6%
Under 52.5 points48%+107-110-7.8%

Note: Green value means the price pays more than our fair price. We only call it a value pick from 3% up, because small gaps can be noise.

Spread and total at every line

Cardinals spreadCoversFair
Cardinals -0.531%+221
Cardinals +3.542%+136
Cardinals +6.551%-105
Cardinals +9.560%-149
Cardinals +13.571%-242
Total pointsOverUnder
45.569%31%
49.558%42%
52.549%51%
55.540%60%
59.528%72%

Note: A spread gives one team a head start. Cardinals +3.5 wins if Cardinals win or lose by 3 or fewer. If the result lands exactly on the line, your stake comes back.

Latest news on these teams

All news
NFL

African Stars Shine in NFL Week 3 as Izien Leads Lions

Detroit Lions safety Christian Izien led a stellar defensive week for NFL players with African ties during Week 3 action.

30 Sept 2026
NFL

Cowboys and Lions Inquire About Steelers Cornerback Joey Porter Jr

The Dallas Cowboys and Detroit Lions have contacted the Pittsburgh Steelers about a trade for cornerback Joey Porter Jr.

27 Sept 2026
NFL

Marvin Harrison Jr. Stays Confident Despite Slow Start With Cardinals

Arizona Cardinals receiver Marvin Harrison Jr. remains confident in his process despite a slow start to the season and mounting outside noise.

24 Sept 2026

Questions people ask

Who will win Detroit Lions vs Arizona Cardinals?

Our prediction for Detroit Lions vs Arizona Cardinals is Detroit Lions to win, with a 69% chance. We project Detroit Lions 29.1 and Arizona Cardinals 23.0. Our best bet is Lions to win at -245.

What is the projected score for Detroit Lions vs Arizona Cardinals?

We project Detroit Lions 29.1 and Arizona Cardinals 23.0, about 52.1 points in total.

How are Arizona Cardinals playing?

Arizona Cardinals have 3 wins and 17 losses in their last 20 games, with 444 points scored and 618 conceded. At home they have 0 wins and 9 losses from 9. Their last 5 results read L, L, W, L, L, newest first.

How are Detroit Lions playing?

Detroit Lions have 11 wins and 9 losses in their last 20 games, with 527 points scored and 475 conceded. Away from home they have 4 wins and 6 losses from 10. Their last 5 results read W, L, W, W, W, newest first.

What is the best bet for Detroit Lions vs Arizona Cardinals?

Lions to win at -245, with a 69% chance.

Note: Answers change as prices move. We check every game again every 30 minutes.

Important, please read before you bet

  • These are opinions, not results. Everything on this page is a probability worked out by a computer model from past games and current prices. No one can know what will happen in Cardinals against Lions. A pick at 70 percent still loses about 3 times in every 10.
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